Microbial Communication via Quorum Sensing: Influence and Alteration of Gut Ecosystem

Background: The cellular communications has been found to regulate numerous microbial events and plays a crucial role in elicitating microbial diversity within the population and overall changes in the surrounding environment. The presence and role of species-specific and inter-species microorganism cell to cell communication and the intrinsic networking of communication within an organization has been recently accepted. It has now been widely accepted that the cellular communications within the microbial system plays an important role in the healthy well-being and as well as in networking. Objective: The mammalian digestive tract contains rich and diverse microbiota on its length. However, extensive studies have been reported on the role and variety of microorganism communities within the gut, scanty work has been reported on QS within the commensal and pathogenic microflora of the tract, with reference to the mode of pathogenesis and infection within the GI tract. The sole patent as of today related to the role of QS in GI tract is said to be on the detection of Lactobacillus strain within the GI Tract. Conclusion: The potential role for QS in GI infections and interaction with commensal microflora is also a very important strategy for the hindrance and treatment.